CJC-1295 without DAC (also sold as "Mod GRF 1-29" or plain "CJC-1295") is a 29-amino-acid analog of growth-hormone-releasing hormone carrying four substitutions for enzymatic stability, but it does not include the maleimidopropionic acid linker — the Drug Affinity Complex, or DAC — that lets the long-acting CJC-1295 DAC variant bind serum albumin and persist for days. That single structural difference is also the most common sourcing hazard: because the two variants share a name and a GHRH-analog core, listings that drop the "no-DAC" qualifier or mislabel inventory can leave a lab running an assay designed around one variant's half-life with the other variant in the vial. See CJC-1295 DAC vs. no-DAC for the full comparison.
What to verify before ordering
- Purity ≥98% by HPLC — method and column conditions disclosed, not a bare percentage. Background: HPLC purity analysis.
- Mass spectrometry identity confirmation that rules out the DAC linker — the no-DAC and DAC variants differ by a well-defined mass, so a mass-spec result confirming the lighter, linker-free molecular weight is the only reliable way to confirm which variant actually shipped. See HPLC vs. mass spectrometry.
- Explicit "no-DAC" labeling on the COA and vial — not generic "CJC-1295" naming that could describe either variant. See CJC-1295 no-DAC chemical structure.
- Batch-specific Certificate of Analysis — tied to the lot actually shipped. See how to read a COA.
- Correct lyophilized form with compound-specific storage guidance. See reconstitution and storage.
Why sourcing discipline matters more for this variant
Because the no-DAC and DAC forms are built on the same GHRH-analog backbone described in the mechanism of action profile and differ only in whether the albumin-binding linker is attached, a vial that is ambiguously labeled can pass a basic "is this a peptide" check while still being the wrong variant for the study's design. Mass-spec confirmation of the specific no-DAC molecular weight, cross-checked against a batch-matched COA, is what actually closes that gap. Our purity testing page covers the analytical methods in more detail.
Questions worth asking any supplier
- Does the COA and vial label explicitly state "without DAC," rather than using "CJC-1295" ambiguously?
- Was identity confirmed by mass spectrometry at a molecular weight consistent with the no-DAC (linker-free) form? See third-party testing explained.
- Is the COA generated per production batch, with a lot number matching the vial received?
- Does the supplier disclose synthesis method and purification steps when asked directly?
- Is sale explicitly restricted to research use, with no dosing or administration guidance implying otherwise?
A supplier that answers these without hedging, and produces a batch-specific, variant-explicit COA on request, is operating the way a laboratory reagent supplier should. Ambiguous labeling or a refusal to confirm which variant shipped is a reason to source elsewhere.
Price relative to documentation
Because the no-DAC variant skips the albumin-binding conjugation step required for the DAC form, it is generally simpler and less costly to synthesize correctly than CJC-1295 DAC — but that doesn't lower the bar for purity and identity testing on the finished peptide itself. Pricing that seems unusually low while still claiming ≥98% HPLC purity and mass-spec-confirmed identity is worth a direct COA request before assuming the claim holds. For criteria that apply across any research peptide order, see the supplier checklist.
Where to buy documented CJC-1295 (no-DAC)
V8 Peptides supplies CJC-1295 without DAC as a lyophilized powder verified to ≥98% purity by HPLC with mass-spectrometry-confirmed identity at the correct no-DAC molecular weight, accompanied by a batch-specific Certificate of Analysis with every order, shipped domestically. The vial is available on the CJC-1295 (no-DAC) research vial product page.
Research Use Only. Supplied strictly for laboratory research and development — not for human or veterinary use, consumption, or any therapeutic or diagnostic purpose. This article is research education, not usage guidance.