Quick answer
A CJC-1295 & ipamorelin blend should come with a batch-specific CoA showing separate purity and identity results for both peptides, and a clear statement that the CJC-1295 is the No-DAC form.
- Masses to expect: CJC-1295 No-DAC about 3,368 Da; ipamorelin about 712 Da
- Must-haves: per-component HPLC purity, mass-spec identity, lot number matching the vial
- Listing: V8 blend page lists ≥98% HPLC purity, 5/5 mg and 10/10 mg sizes
- Concentration: mg ÷ mL for each component; use the calculator
- Documents: CoA library
For laboratory research use only; not for human consumption.
What you are actually sourcing
A CJC-1295 (No-DAC) and ipamorelin blend is two distinct synthetic peptides in one vial. CJC-1295 without DAC (also called modified GRF 1-29) is a 30-residue analog of growth-hormone-releasing hormone with a mass of about 3,368 Da. Ipamorelin is a five-residue pentapeptide, Aib-His-D-2-Nal-D-Phe-Lys-NH2, with a mass of about 712 Da (C38H49N9O5), that acts as a selective ghrelin-receptor agonist in research models. They work through different receptors, which is the reason they are studied together; the pairing is described in the CJC-1295 & ipamorelin overview and the blend explainer.
For a buyer, the practical consequence is that verification has to cover both components. A supplier can easily document one peptide well and say little about the other, so the checks below are written for a two-component product. Sourcing a single-peptide vial is covered separately in where to buy ipamorelin and where to buy CJC-1295 No-DAC.
| Component | Residues | Approx. average mass | Notable feature |
|---|---|---|---|
| CJC-1295 (No-DAC) | 30 | About 3,368 Da | Four substitutions relative to native GHRH(1-29) that improve stability; C-terminal amide |
| Ipamorelin | 5 | About 712 Da | Contains Aib and two D-residues, which resist peptidases |
The DAC question: confirm which CJC-1295 is in the vial
CJC-1295 exists in two forms. The No-DAC form is the unmodified 30-residue peptide. The DAC form carries a drug affinity complex, a lysine-linked maleimide-based group that binds serum albumin and greatly extends half-life. The two have materially different research profiles, mass and chromatographic behavior, and the comparison is set out in CJC-1295 DAC vs. No-DAC. A listing should state which one it is. The V8 product is the No-DAC form, as its name says: CJC-1295 (No-DAC) + ipamorelin blend.
The simplest independent check is mass. A No-DAC reading near 3,368 Da is expected; a DAC construct would be substantially heavier. If a certificate shows no CJC-1295 mass at all, the DAC question cannot be answered from the document.
What to check before buying a blend
- Purity reported per component. A trustworthy listing states a measured purity value (the V8 page lists ≥98% HPLC purity) with the method named, and the certificate should show each peptide as its own resolved peak, not one blended figure that could hide a shortfall in either.
- A batch-specific certificate of analysis. The document should correspond to the production lot in the vial and show chromatography and mass-spectrometry results for both CJC-1295 and ipamorelin, not a generic template reused across batches.
- Independent verification. In-house testing is a starting point, not a substitute for confirmation by an outside analytical lab. See third-party testing explained.
- Clear labeling of the stated amounts. The product page lists 5 mg / 5 mg and 10 mg / 10 mg presentations, meaning each component is present at the stated amount. A label that gives only a combined number leaves the ratio unclear.
- Honest storage and reconstitution information rather than vague or absent handling notes.
- Research-use-only labeling with no suggestion of human or veterinary application anywhere in the listing.
- Shipping practices appropriate for a lyophilized peptide. See how research peptides are shipped.
Why documentation matters more for a blend
With a single-peptide product, a missing or vague certificate is already a red flag. With a two-component blend the risk compounds. An incomplete report might disclose purity for one peptide while omitting the other, or present a combined figure that obscures which component falls short. Reviewing a sample certificate line by line, checking that both peptides appear with independent purity and identity results, is worth doing before ordering and not after. Reading guidance for each field is in how to read a CoA.
The analytical reasoning is specific to this pair. Because the two molecules differ by roughly 2,650 Da, mass spectrometry separates them trivially, and a competent report shows two clearly identified species. Chromatographically, the smaller, more hydrophobic ipamorelin and the larger, more charged CJC-1295 elute at different times, so one trace can quantify both. Details on what to expect are in CJC-1295 & ipamorelin purity testing, with the single-component references CJC-1295 DAC purity testing and ipamorelin purity testing.
Reading a sample certificate for a blend
| Certificate element | Good sign | Warning sign |
|---|---|---|
| Lot number | Matches the number on the vial | Absent, or different from the vial |
| HPLC trace | Two resolved main peaks, method stated | Single peak, or no trace shown |
| Purity | Reported for each component | One combined figure only |
| Mass spectrum | Observed masses near 3,368 Da and 712 Da | No mass data, or masses that fit a DAC construct without saying so |
| Test date and lab | Both present | Neither stated |
Common red flags
Listings priced well below the rest of the market for a stated purity level, vials with no lot number printed anywhere, or a certificate that is clearly a generic PDF unconnected to any specific batch are all reasons to look elsewhere. None of these signs is proof of a problem on its own, but together they describe a listing that skips the verification work described above. The full list is in red flags when buying research peptides, and the general framework is in choosing a research peptide supplier and how to buy research peptides online.
Planning for handling before you order
A blend is a fixed-ratio mixture, so whatever you do with it applies to both peptides at once. Plan the stock concentration in advance. A 5 mg / 5 mg vial holds 10 mg of total peptide; reconstituted in 2 mL, that is 5 mg/mL total, or 2.5 mg/mL of each component. The peptide calculator performs the same arithmetic for any vial size and diluent volume. Remember that net peptide content is lower than gross powder mass because of counter-ions and moisture.
Storage guidance on the product page is 2–8 °C, or −20 °C for the long term, protected from heat, moisture and light. Handling after reconstitution is covered in CJC-1295 & ipamorelin reconstitution and storage.
Where to find a documented CJC-1295 & ipamorelin blend
V8 Peptides supplies the CJC-1295 (No-DAC) & ipamorelin blend as a lyophilized powder in a sealed glass research vial, listed at ≥98% HPLC purity, with batch-specific documentation. The page notes that identity, purity, lot number and test date are the fields documented. Published certificates are in the CoA library, and the badge on the product page shows whether the certificate for a given lot has been posted yet, so check it for the lot you receive. Shipping is by USPS in discreet packaging, as stated on the page.
Research Use Only. For laboratory research use only; not for human consumption. This article is research education, not usage guidance.
Frequently asked questions
Should purity be reported for both peptides in a blend?
Yes. A single combined figure can hide a shortfall in either component. A proper report shows CJC-1295 and ipamorelin as separate peaks with separate purity and identity data.
How can I tell No-DAC CJC-1295 from the DAC form?
By label and by mass. No-DAC CJC-1295 is about 3,368 Da; the DAC form is substantially heavier because of the albumin-binding group. The listing must say which is in the vial.
What does 5 mg / 5 mg mean on a blend listing?
Each of the two peptides is present at 5 mg, so the vial holds 10 mg of total peptide. A 10 mg / 10 mg vial holds 20 mg.
Is in-house testing enough?
It is a start, but independent third-party analysis is stronger evidence. See the third-party testing article for what to look for.
How do I work out the concentration of each component after reconstitution?
Divide each component's mass by the diluent volume. A 5 mg / 5 mg vial in 2 mL gives 2.5 mg/mL of each peptide. The calculator does this for any combination.
Why is mass spectrometry easy for this pair?
Their masses differ by about 2,650 Da, so a spectrum separates them clearly and confirms both are present.
What are the storage conditions for this blend?
The product page states 2–8 °C, or −20 °C for long-term storage, protected from heat, moisture and light.
What are the warning signs on a certificate?
No lot number, no mass data, one combined purity figure, no named lab or test date, or an identical certificate shared across products.
References
- V8 Peptides. CJC-1295 & ipamorelin: discovery and history.
- V8 Peptides. Choosing a research peptide supplier.
- V8 Peptides. Red flags when buying research peptides.
- V8 Peptides. CJC-1295 & ipamorelin purity testing.
- V8 Peptides. CJC-1295 (No-DAC) + ipamorelin blend: product specifications.