Semax combines an ACTH-fragment core with a stabilizing C-terminal extension, and verifying both parts are correctly synthesized is the point of lot-level analytical testing.
Reversed-phase HPLC
HPLC separates the fully extended peptide from truncated forms lacking the Pro-Gly-Pro stabilizing addition, with purity read per understanding HPLC purity.
Mass spectrometry for identity
Mass spectrometry confirms the molecule's mass matches semax's complete extended sequence described in its chemistry article, distinguishing it from the unmodified ACTH(4-10) fragment — general background is in HPLC vs. mass spectrometry.
Why the extension is the whole point
Semax's practical research utility comes entirely from the stability its extension provides (see its mechanism of action); an incompletely synthesized lot loses that advantage and would behave more like a short-lived native fragment, similar to the stabilization logic behind selank.
Documentation to expect
A lot-specific certificate of analysis with HPLC purity and mass-spec identity — see how to read a CoA.
Product page: Semax research vials.
Research Use Only. Supplied strictly for laboratory research and development — not for human or veterinary use, consumption, or any therapeutic or diagnostic purpose. This article is research education, not usage guidance.