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TB-500 Chemical Structure & Synthesis
TB-500Chemistry

TB-500 Chemical Structure & Synthesis

July 30, 2026

TB-500 is a synthetic peptide corresponding to an active region of Thymosin Beta-4, a naturally occurring 43-amino-acid protein involved in actin regulation.

Structure

Rather than reproduce the full Thymosin Beta-4 protein, TB-500 focuses on the active sequence associated with actin-binding, giving researchers a stable, synthesizable peptide. The actin-regulation link is central to its mechanism of action.

How it is made

TB-500 is produced by solid-phase peptide synthesis, then purified and verified by HPLC and mass spectrometry. See the TB-500 overview.

Available in the BPC-157 + TB-500 research stack.

Research Use Only. Supplied strictly for laboratory research and development — not for human or veterinary use, consumption, or any therapeutic or diagnostic purpose. This article is research education, not usage guidance.

Research Use Only. All products are sold strictly for laboratory research and development purposes only. Not for human or animal consumption. Not a drug, food, or cosmetic. By purchasing, you affirm you are a qualified researcher or institution.