Cagrilintide

What is cagrilintide?

Cagrilintide is a synthetic, long-acting analog of amylin, the 37-amino-acid peptide hormone that pancreatic beta cells release together with insulin. The analog carries a fatty-acid side chain, a lipidation strategy that promotes albumin binding and lengthens the time the molecule persists in experimental systems. It is supplied here as lyophilized powder in a sealed 10 mg vial.

Researchers use cagrilintide as a tool compound for amylin- and calcitonin-receptor pharmacology. It also appears in comparative work alongside incretin-pathway peptides, where investigators examine how amylin-receptor and GLP-1-receptor signaling interact in preclinical metabolic models.

Where it is used in the lab

• Amylin- and calcitonin-receptor binding and signaling assays
• Combination studies with incretin-pathway peptides in preclinical models
• Stability and formulation analytics for lipidated peptides

For laboratory research use only; not for human consumption.

Cagrilintide specifications

Reconstitution & storage for research

Concentration is a simple ratio of vial content to diluent volume. Adding 2 mL of diluent to the 10 mg vial gives 5 mg/mL; 4 mL gives 2.5 mg/mL, and 1 mL gives 10 mg/mL. At 5 mg/mL, a 50 µL aliquot contains 250 µg. To check a different volume, enter the vial size into the reconstitution calculator.

A sterile diluent such as bacteriostatic water is the usual choice for multi-use research vials. Add diluent gradually against the glass, allow the cake to dissolve on its own for a minute or two, and finish with a slow swirl. Shaking is unnecessary and can introduce foam. Lipidated peptides tend to foam, so patience during dissolution pays off in a cleaner solution.

Storage conditions

• Lyophilized powder: 2–8 °C for routine storage, −20 °C for long-term holding.
• Protection: shield the vial from light, humidity and temperature swings; store it upright in its box.
• Solution: keep refrigerated, record the lot number and concentration on the vial, and avoid repeated freeze–thaw cycles by aliquoting once.

Quality & testing

Cagrilintide is released only after HPLC analysis confirms purity of ≥98%. Each batch has its own Certificate of Analysis; find it by lot number on the COA page and file a copy with your receiving records.

• HPLC purity value for that specific lot
• Compound identity verification
• Lot number tied to the label on your vial
• Date of analysis, supplied form and storage guidance

Orders ship from the US in discreet packaging, with each vial labeled for research use. We accept payment by invoice or Zelle.

Related lab guides

• Cagrilintide research overview
• Cagrilintide reconstitution and storage
• How cagrilintide purity is tested
• Cagrilintide vs. pramlintide
• Cagrilintide and semaglutide combination research
• Reconstitution calculator guide

Incretin-pathway peptides frequently studied next to amylin analogs: Semaglutide, Tirzepatide, Retatrutide.