NAD+ (nicotinamide adenine dinucleotide) is a coenzyme present in every cell, which makes it a broad object of study across several distinct research areas.
Energy metabolism
NAD+ is central to redox reactions that move electrons through core metabolic pathways, cycling between its oxidized (NAD+) and reduced (NADH) forms. Bioenergetics research examines this cycling in cell models.
Sirtuins and signaling
NAD+ is a required substrate for sirtuins, a family of enzymes studied in aging- and stress-response signaling. Because sirtuin activity depends on NAD+ availability, researchers study how the coenzyme's levels influence these pathways.
DNA repair
NAD+ is also consumed by PARP enzymes involved in DNA-damage response, another active research area. For the broader picture, see NAD+ in cellular research.
Product page: NAD+ research vials.
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