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GHK-Cu Chemical Structure & Synthesis
GHK-CuChemistry

GHK-Cu Chemical Structure & Synthesis

July 31, 2026

GHK-Cu is a small copper-binding tripeptide — glycyl-L-histidyl-L-lysine (GHK) complexed with a copper(II) ion — making it structurally distinct from the larger peptides in the catalog.

The tripeptide backbone

GHK is just three amino acids, but the histidine imidazole and terminal amine give it a natural affinity for copper. Background on sequences: understanding amino acid sequences.

Copper coordination

The defining feature is the copper(II) complex; the metal is coordinated by the peptide, and this Cu binding is central to the biology explored in GHK-Cu mechanism of action and copper-peptide research.

Preparation and verification

The peptide is made by solid-phase synthesis and then complexed with a copper salt; identity and purity are confirmed by HPLC and mass spectrometry.

Product page: GHK-Cu research vials.

Research Use Only. Supplied strictly for laboratory research and development — not for human or veterinary use, consumption, or any therapeutic or diagnostic purpose. This article is research education, not usage guidance.

Research Use Only. All products are sold strictly for laboratory research and development purposes only. Not for human or animal consumption. Not a drug, food, or cosmetic. By purchasing, you affirm you are a qualified researcher or institution.