AOD-9604 is a modified 16-residue hGH fragment, and confirming a given lot matches that exact sequence is the analytical basis for treating a study's results as attributable to the compound itself.
Reversed-phase HPLC
HPLC separates the target fragment from truncated sequences and other solid-phase-synthesis byproducts, with the resulting purity read per understanding HPLC purity.
Mass spectrometry for identity
Because AOD-9604 is a fragment rather than a full-length protein, mass spectrometry is particularly useful for confirming the fragment boundary and the added N-terminal tyrosine described in its chemistry article are both correct — see HPLC vs. mass spectrometry.
Why it matters for isolating a metabolic signal
AOD-9604's research premise is that it isolates a specific metabolic-signaling fragment from growth hormone's broader activity (see its mechanism of action); an impure lot risks reintroducing exactly the confounding activity the fragment was designed to avoid.
Documentation to expect
A lot-specific certificate of analysis with HPLC purity and mass-spec identity — see how to read a CoA.
Product page: AOD-9604 research vials.
Research Use Only. Supplied strictly for laboratory research and development — not for human or veterinary use, consumption, or any therapeutic or diagnostic purpose. This article is research education, not usage guidance.
