GHK-Cu + KPV

What is the GHK-Cu + KPV blend?

This product combines two short peptides in a single lyophilized vial. GHK-Cu is the copper(II) complex of the tripeptide Gly-His-Lys, first isolated from human plasma. KPV is the tripeptide Lys-Pro-Val, which corresponds to the last three residues (11–13) of alpha-melanocyte-stimulating hormone (α-MSH). The vial holds 60 mg of blended material in total.

A pre-blended format is useful when a study design calls for both components at a fixed ratio, because it removes one source of pipetting variation between replicates. Researchers working with dermal cell cultures use the pairing to look at copper-peptide signaling and melanocortin-derived tripeptide signaling in the same experiment, then compare against each component run alone.

Where it is used in the lab

• Copper-peptide signaling studies in dermal cell cultures
• Melanocortin-fragment (KPV) experiments with NF-κB pathway readouts
• Blend-versus-single-component comparison designs

For laboratory research use only; not for human consumption.

GHK-Cu + KPV specifications

Reconstitution & storage for research

For a blend, calculate the total concentration first. Adding 3 mL of diluent to the 60 mg vial gives 20 mg/mL of total blend; adding 2 mL gives 30 mg/mL. To find the concentration of each component, multiply the total by that component's share of the 60 mg as stated on the batch COA. A blue tint from the copper complex is normal. To check a different volume, enter the vial size into the reconstitution calculator.

A sterile diluent such as bacteriostatic water is the usual choice for multi-use research vials. Add diluent gradually against the glass, allow the cake to dissolve on its own for a minute or two, and finish with a slow swirl. Shaking is unnecessary and can introduce foam.

Storage conditions

• Lyophilized powder: 2–8 °C for routine storage, −20 °C for long-term holding.
• Protection: shield the vial from light, humidity and temperature swings; store it upright in its box.
• Solution: keep refrigerated, record the lot number and concentration on the vial, and avoid repeated freeze–thaw cycles by aliquoting once.

Quality & testing

GHK-Cu + KPV is released only after HPLC analysis confirms purity of ≥98%. Each batch has its own Certificate of Analysis; find it by lot number on the COA page and file a copy with your receiving records.

• HPLC purity value for that specific lot
• Compound identity verification
• Lot number tied to the label on your vial
• Date of analysis, supplied form and storage guidance

Orders ship from the US in discreet packaging, with each vial labeled for research use. We accept payment by invoice or Zelle.

Related lab guides

• GHK-KPV research overview
• GHK-KPV reconstitution and storage
• GHK-KPV purity testing and identity verification
• GHK-KPV structure and synthesis
• Peptide blends and research stacks
• Reconstitution calculator guide

The individual components, and a larger blend, are available separately: GHK-Cu, KPV, KLOW stack.